Entity Details

Primary name BRSK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWQ3
EntryNameBRSK2_HUMAN
FullNameSerine/threonine-protein kinase BRSK2
TaxID9606
Evidenceevidence at protein level
Length736
SequenceStatuscomplete
DateCreated2003-08-29
DateModified2021-06-02

Ontological Relatives

GenesBRSK2

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000287 magnesium ion binding
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0006468 protein phosphorylation
GO:0006887 exocytosis
GO:0007409 axonogenesis
GO:0010975 regulation of neuron projection development
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030010 establishment of cell polarity
GO:0030182 neuron differentiation
GO:0031532 actin cytoskeleton reorganization
GO:0035556 intracellular signal transduction
GO:0036503 ERAD pathway
GO:0042149 cellular response to glucose starvation
GO:0043462 regulation of ATPase activity
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0050321 tau-protein kinase activity
GO:0050770 regulation of axonogenesis
GO:0051117 ATPase binding
GO:0051301 cell division
GO:0060590 ATPase regulator activity
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0150034 distal axon
GO:1904152 regulation of retrograde protein transport, ER to cytosol
GO:2000807 regulation of synaptic vesicle clustering

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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