Entity Details

Primary name RHG12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWW6
EntryNameRHG12_HUMAN
FullNameRho GTPase-activating protein 12
TaxID9606
Evidenceevidence at protein level
Length846
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesARHGAP12

GO terms

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GOName
GO:0001891 phagocytic cup
GO:0002011 morphogenesis of an epithelial sheet
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006911 phagocytosis, engulfment
GO:0007015 actin filament organization
GO:0007165 signal transduction
GO:0043087 regulation of GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051058 negative regulation of small GTPase mediated signal transduction

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001202 WW domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035491 ARHGAP12, SH3 domainDomainDomain
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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