Entity Details

Primary name CKP2L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IYA6
EntryNameCKP2L_HUMAN
FullNameCytoskeleton-associated protein 2-like
TaxID9606
Evidenceevidence at protein level
Length745
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesCKAP2L

GO terms

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GOName
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005829 cytosol
GO:0072686 mitotic spindle

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR029197 Cytoskeleton-associated protein 2, C-terminalDomainDomain

Diseases

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Disease IDSourceNameDescription
272440 OMIMFilippi syndrome (FLPIS)A rare disorder characterized by microcephaly, pre- and postnatal growth failure, syndactyly, and distinctive facial features, including a broad nasal bridge and underdeveloped alae nasi. Some affected individuals have intellectual disability, seizures, undescended testicles in males, and teeth and hair abnormalities. The disease is caused by variants affecting the gene represented in this entry.

Interactions

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