Entity Details

Primary name CMTR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N1G2
EntryNameCMTR1_HUMAN
FullNameCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length835
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesCMTR1

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006370 7-methylguanosine mRNA capping
GO:0043231 intracellular membrane-bounded organelle
GO:0080009 mRNA methylation
GO:0097309 cap1 mRNA methylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000467 G-patch domainDomainDomain
IPR001202 WW domainDomainDomain
IPR002877 Ribosomal RNA methyltransferase FtsJ domainDomainDomain
IPR025816 RrmJ-type ribose 2-O-methyltransferase domainDomainDomain
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR030376 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00118 AdemetionineDrugbanksmall molecule