Entity Details

Primary name LIRB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N423
EntryNameLIRB2_HUMAN
FullNameLeukocyte immunoglobulin-like receptor subfamily B member 2
TaxID9606
Evidenceevidence at protein level
Length598
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0002250 adaptive immune response
GO:0002578 negative regulation of antigen processing and presentation
GO:0002645 positive regulation of tolerance induction
GO:0002666 positive regulation of T cell tolerance induction
GO:0002767 immune response-inhibiting cell surface receptor signaling pathway
GO:0002774 Fc receptor mediated inhibitory signaling pathway
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007611 learning or memory
GO:0008157 protein phosphatase 1 binding
GO:0009986 cell surface
GO:0016020 membrane
GO:0023025 MHC class Ib protein complex binding
GO:0023029 MHC class Ib protein binding
GO:0032396 inhibitory MHC class I receptor activity
GO:0032755 positive regulation of interleukin-6 production
GO:0034113 heterotypic cell-cell adhesion
GO:0035307 positive regulation of protein dephosphorylation
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0042288 MHC class I protein binding
GO:0042803 protein homodimerization activity
GO:0043312 neutrophil degranulation
GO:0044877 protein-containing complex binding
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0050776 regulation of immune response
GO:0050839 cell adhesion molecule binding
GO:0051248 negative regulation of protein metabolic process
GO:0051926 negative regulation of calcium ion transport
GO:0070821 tertiary granule membrane
GO:0071222 cellular response to lipopolysaccharide
GO:0101003 ficolin-1-rich granule membrane
GO:0140105 interleukin-10-mediated signaling pathway
GO:1900271 regulation of long-term synaptic potentiation
GO:1900454 positive regulation of long-term synaptic depression
GO:1905875 negative regulation of postsynaptic density organization
GO:2000524 negative regulation of T cell costimulation
GO:2001198 regulation of dendritic cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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