Entity Details

Primary name SYT14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NB59
EntryNameSYT14_HUMAN
FullNameSynaptotagmin-14
TaxID9606
Evidenceevidence at protein level
Length555
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesSYT14

GO terms

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GOName
GO:0016021 integral component of membrane

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR028696 Synaptotagmin-14FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR043541 Synaptotagmin-14/14L/16FamilyFamily

Diseases

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Disease IDSourceNameDescription
614229 OMIMSpinocerebellar ataxia, autosomal recessive, 11 (SCAR11)A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR11 is associated with psychomotor retardation. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SYT14_HUMANSYT16_HUMANBioGRID, HPRD12801916 details
SYT14_HUMANSYT14_HUMANHPRD12801916 details