Entity Details

Primary name TXND5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NBS9
EntryNameTXND5_HUMAN
FullNameThioredoxin domain-containing protein 5
TaxID9606
Evidenceevidence at protein level
Length432
SequenceStatuscomplete
DateCreated2003-04-11
DateModified2021-06-02

Ontological Relatives

GenesTXNDC5

GO terms

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GOName
GO:0003756 protein disulfide isomerase activity
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0006892 post-Golgi vesicle-mediated transport
GO:0035578 azurophil granule lumen
GO:0043066 negative regulation of apoptotic process
GO:0043202 lysosomal lumen
GO:0043277 apoptotic cell clearance
GO:0043312 neutrophil degranulation
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Endoplasmic reticulum lumen

Domains

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DomainNameCategoryType
IPR005788 Disulphide isomeraseDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR017937 Thioredoxin, conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
TXND5_HUMANPRDX4_HUMANMINT21057456 details
TXND5_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
TXND5_HUMANNT2NA_HUMANBioGRID, IntAct25416956 31515488 details
TXND5_HUMANGMPPB_HUMANBioGRID, IntAct25416956 31515488 details
TXND5_HUMANKRT38_HUMANBioGRID, IntAct25416956 29892012 details
TXND5_HUMANA4_HUMANBioGRID21832049 details
TXND5_HUMANTRI23_HUMANBioGRID25416956 details
TXND5_HUMANFBLN3_HUMANBioGRID25416956 27777122 details
TXND5_HUMANTRIP6_HUMANBioGRID25416956 details
TXND5_HUMANGO45_HUMANBioGRID25416956 details
TXND5_HUMANSPY2_HUMANBioGRID25416956 details
TXND5_HUMANKR412_HUMANBioGRID25416956 details
TXND5_HUMANKRA42_HUMANBioGRID25416956 details
TXND5_HUMANLHX4_HUMANBioGRID25416956 details
TXND5_HUMANK1C40_HUMANBioGRID25416956 details
TXND5_HUMANFACC1_HUMANBioGRID25416956 details
TXND5_HUMANMGT5B_HUMANBioGRID25416956 details
TXND5_HUMANTRI42_HUMANBioGRID25416956 details
TXND5_HUMANKR107_HUMANBioGRID25416956 details
TXND5_HUMANKR109_HUMANBioGRID25416956 details
TXND5_HUMANKR108_HUMANBioGRID25416956 details
TXND5_HUMANKR103_HUMANBioGRID25416956 details
TXND5_HUMANNT2NC_HUMANBioGRID25416956 details
TXND5_HUMANRAB3I_HUMANBioGRID21516116 details
TXND5_HUMANPJA1_HUMANBioGRID21461837 details
TXND5_HUMANANDR_HUMANBioGRID25500540 details
TXND5_HUMANEDEM3_HUMANBioGRID29784879 details
TXND5_HUMANPRDX2_HUMANBioGRID23713588 details
TXND5_HUMANOGT1_HUMANBioGRID32994395 details
TXND5_HUMANDCAF7_HUMANBioGRID, IntAct27173435 unassigned1312 details
TXND5_HUMANHSP74_HUMANBioGRID25500540 details
TXND5_HUMANA1AT_HUMANBioGRID29784879 details
TXND5_HUMANTULP3_HUMANBioGRID33187986 details