Entity Details

Primary name SEN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NCE0
EntryNameSEN2_HUMAN
FullNametRNA-splicing endonuclease subunit Sen2
TaxID9606
Evidenceevidence at protein level
Length465
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesTSEN2

GO terms

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GOName
GO:0000213 tRNA-intron endonuclease activity
GO:0000214 tRNA-intron endonuclease complex
GO:0000379 tRNA-type intron splice site recognition and cleavage
GO:0003676 nucleic acid binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006397 mRNA processing
GO:0016829 lyase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006676 tRNA-splicing endonucleaseFamilyFamily
IPR006677 tRNA intron endonuclease, catalytic domain-likeDomainDomain
IPR006678 tRNA intron endonuclease, N-terminalDomainDomain
IPR011856 tRNA endonuclease-like domain superfamilyFamilyHomologous superfamily
IPR016589 tRNA-splicing endonuclease, SEN2 subunitFamilyFamily
IPR036167 tRNA intron endonuclease, catalytic domain-like superfamilyFamilyHomologous superfamily

Diseases

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