Entity Details

Primary name EHBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NDI1
EntryNameEHBP1_HUMAN
FullNameEH domain-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length1231
SequenceStatuscomplete
DateCreated2007-05-01
DateModified2021-06-02

Ontological Relatives

GenesEHBP1

GO terms

Show/Hide Table
GOName
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0030036 actin cytoskeleton organization
GO:0031941 filamentous actin

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endosome
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001715 Calponin homology domainDomainDomain
IPR019448 NT-type C2 domainDomainDomain
IPR022735 bMERB domainDomainDomain
IPR029944 EH domain-binding protein 1FamilyFamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
611868 OMIMProstate cancer, hereditary, 12 (HPC12)A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. Disease susceptibility is associated with variants affecting the gene represented in this entry.