Entity Details

Primary name ADCY4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NFM4
EntryNameADCY4_HUMAN
FullNameAdenylate cyclase type 4
TaxID9606
Evidenceevidence at protein level
Length1077
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesADCY4

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004016 adenylate cyclase activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006171 cAMP biosynthetic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0016020 membrane
GO:0030425 dendrite
GO:0034199 activation of protein kinase A activity
GO:0035556 intracellular signal transduction
GO:0046872 metal ion binding
GO:0071377 cellular response to glucagon stimulus

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR009398 Adenylate cyclase, conserved domainDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily
IPR030672 Adenylate cyclaseFamilyFamily
IPR032628 Adenylate cyclase, N-terminalDomainDomain

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
ADCY4_HUMANTRI54_HUMANBioGRID, IntAct25416956 details
ADCY4_HUMANCA050_HUMANBioGRID, IntAct32296183 details
ADCY4_HUMANERR3_HUMANBioGRID, IntAct32296183 details
ADCY4_HUMANPPARG_HUMANBioGRID, IntAct32296183 details
ADCY4_HUMANTTC23_HUMANBioGRID, IntAct32296183 details