Entity Details

Primary name LIRB4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NHJ6
EntryNameLIRB4_HUMAN
FullNameLeukocyte immunoglobulin-like receptor subfamily B member 4
TaxID9606
Evidenceevidence at protein level
Length448
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesLILRB4

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002507 tolerance induction
GO:0002669 positive regulation of T cell anergy
GO:0002725 negative regulation of T cell cytokine production
GO:0002774 Fc receptor mediated inhibitory signaling pathway
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0019903 protein phosphatase binding
GO:0030293 transmembrane receptor protein tyrosine kinase inhibitor activity
GO:0030547 signaling receptor inhibitor activity
GO:0031623 receptor internalization
GO:0032682 negative regulation of chemokine production
GO:0032689 negative regulation of interferon-gamma production
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032693 negative regulation of interleukin-10 production
GO:0032703 negative regulation of interleukin-2 production
GO:0032714 negative regulation of interleukin-5 production
GO:0032715 negative regulation of interleukin-6 production
GO:0042130 negative regulation of T cell proliferation
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0043409 negative regulation of MAPK cascade
GO:0045584 negative regulation of cytotoxic T cell differentiation
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0045671 negative regulation of osteoclast differentiation
GO:0046007 negative regulation of activated T cell proliferation
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070062 extracellular exosome
GO:0071659 negative regulation of IP-10 production
GO:0098752 integral component of the cytoplasmic side of the plasma membrane
GO:0140105 interleukin-10-mediated signaling pathway
GO:0150102 negative regulation of monocyte activation
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1900181 negative regulation of protein localization to nucleus
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:2000272 negative regulation of signaling receptor activity
GO:2000524 negative regulation of T cell costimulation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
LIRB4_HUMANPTN6_HUMANIntAct18802077 details