Entity Details

Primary name ASM3B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92485
EntryNameASM3B_HUMAN
FullNameAcid sphingomyelinase-like phosphodiesterase 3b
TaxID9606
Evidenceevidence at protein level
Length455
SequenceStatuscomplete
DateCreated2001-08-29
DateModified2021-06-02

Ontological Relatives

GenesSMPDL3B

GO terms

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GOName
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006685 sphingomyelin catabolic process
GO:0006954 inflammatory response
GO:0008081 phosphoric diester hydrolase activity
GO:0008270 zinc ion binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0031225 anchored component of membrane
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0045087 innate immune response
GO:0046466 membrane lipid catabolic process
GO:0050728 negative regulation of inflammatory response
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR004843 Calcineurin-like phosphoesterase domain, ApaH typeDomainDomain
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predictedFamilyFamily
IPR029052 Metallo-dependent phosphatase-likeFamilyHomologous superfamily
IPR041805 Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domainDomainDomain

Diseases

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Interactions

3 interactions