Entity Details

Primary name WNT2B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ93097
EntryNameWNT2B_HUMAN
FullNameProtein Wnt-2b
TaxID9606
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesWNT2B

GO terms

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GOName
GO:0002062 chondrocyte differentiation
GO:0002088 lens development in camera-type eye
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0008584 male gonad development
GO:0009267 cellular response to starvation
GO:0016055 Wnt signaling pathway
GO:0021871 forebrain regionalization
GO:0030182 neuron differentiation
GO:0043231 intracellular membrane-bounded organelle
GO:0045165 cell fate commitment
GO:0060070 canonical Wnt signaling pathway
GO:0060492 lung induction
GO:0060638 mesenchymal-epithelial cell signaling
GO:0061072 iris morphogenesis
GO:0061303 cornea development in camera-type eye
GO:0062023 collagen-containing extracellular matrix
GO:0071425 hematopoietic stem cell proliferation
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR005817 WntFamilyFamily
IPR009140 Wnt-2 proteinFamilyFamily
IPR018161 Wnt protein, conserved siteSiteConserved site
IPR043158 Wnt, C-terminal domainFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
618168 OMIMDiarrhea 9 (DIAR9)An autosomal recessive form of chronic diarrhea characterized by neonatal-onset of osmotic diarrhea that is not substrate specific, abnormal crypt and villus architecture, and significant fat malabsorption evidenced by high levels of fecal fat. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions