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Entity Details
Primary name
UIMC1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96RL1
EntryName
UIMC1_HUMAN
FullName
BRCA1-A complex subunit RAP80
TaxID
9606
Evidence
evidence at protein level
Length
719
SequenceStatus
complete
DateCreated
2005-03-01
DateModified
2021-06-02
Ontological Relatives
Genes
UIMC1
GO terms
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GO
Name
GO:0003677
DNA binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0006302
double-strand break repair
GO:0006303
double-strand break repair via nonhomologous end joining
GO:0010212
response to ionizing radiation
GO:0016579
protein deubiquitination
GO:0016604
nuclear body
GO:0042393
histone binding
GO:0045739
positive regulation of DNA repair
GO:0045892
negative regulation of transcription, DNA-templated
GO:0046872
metal ion binding
GO:0070530
K63-linked polyubiquitin modification-dependent protein binding
GO:0070531
BRCA1-A complex
GO:0070537
histone H2A K63-linked deubiquitination
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR003903
Ubiquitin interacting motif
Site
Conserved site
IPR006642
Rad18, zinc finger UBZ4-type
Domain
Domain
IPR038868
BRCA1-A complex subunit RAP80
Family
Family
IPR040714
RAP80, N-terminal
Domain
Domain
Diseases
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Drugs
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Interactions
44 interactions
Interactor
Partner
Sources
Publications
Link
UIMC1_HUMAN
SKIL_HUMAN
BioGRID, HPRD, MINT
15231748
details
UIMC1_HUMAN
IN80B_HUMAN
HPRD, IntAct
16169070
details
UIMC1_HUMAN
BRCA1_HUMAN
BioGRID, DIP, IntAct, UniProt
17525340
17525341
17525342
17621610
17643121
19261748
19305427
19615732
19766185
21622030
24085845
25184681
25252691
26027929
26446986
28569838
29499138
29656893
31932421
details
UIMC1_HUMAN
ABRX1_HUMAN
BioGRID, DIP, HPRD, IntAct
17525340
17643121
17643122
18077395
19015238
19261746
19261748
19261749
19305427
19615732
20656689
20656690
21282113
22357538
23264621
24075985
25252691
28242625
28569838
details
UIMC1_HUMAN
UBC9_HUMAN
IntAct
19549727
details
UIMC1_HUMAN
BRCC3_HUMAN
BioGRID, DIP, IntAct
17525341
18077395
19015238
19202061
19261746
19261748
19261749
19305427
19615732
20656689
21282113
23264621
details
UIMC1_HUMAN
BABA2_HUMAN
BioGRID, IntAct
17525341
19015238
19261746
19261748
19261749
19615732
20656689
21282113
details
UIMC1_HUMAN
BABA1_HUMAN
BioGRID, IntAct
19261746
19261748
19261749
19615732
21282113
26186194
28514442
28569838
details
UIMC1_HUMAN
CDK1_HUMAN
BioGRID, IntAct
19615732
23264621
details
UIMC1_HUMAN
DVL2_HUMAN
BioGRID, IntAct, MINT
21516116
29892012
31515488
details
UIMC1_HUMAN
RD23A_HUMAN
BioGRID, IntAct
19013454
32296183
details
UIMC1_HUMAN
MDC1_HUMAN
BioGRID, DIP, UniProt
21622030
21857162
22990118
24240613
29656893
details
UIMC1_HUMAN
ESR1_HUMAN
BioGRID, IntAct
17311814
31527615
details
UIMC1_HUMAN
DCTN1_HUMAN
IntAct
32814053
details
UIMC1_HUMAN
PRKN_HUMAN
IntAct
32814053
details
UIMC1_HUMAN
RNF11_HUMAN
IntAct
32814053
details
UIMC1_HUMAN
SYUA_HUMAN
IntAct
32814053
details
UIMC1_HUMAN
NR6A1_HUMAN
BioGRID, HPRD
12080054
17416745
details
UIMC1_HUMAN
UBC_HUMAN
BioGRID
17311814
17525341
19015238
19261749
19305427
19536136
19944020
20698691
22350954
22605335
22689573
23211528
23314748
23562397
23823328
24627472
25756347
28082312
28190767
28569838
31699778
details
UIMC1_HUMAN
P53_HUMAN
BioGRID
19433585
details
UIMC1_HUMAN
SUMO2_HUMAN
BioGRID
22689573
23211528
26719330
32786267
details
UIMC1_HUMAN
AT8A2_HUMAN
BioGRID
17621610
details
UIMC1_HUMAN
H2A2C_HUMAN
BioGRID
19015238
25132264
details
UIMC1_HUMAN
C1QBP_HUMAN
BioGRID
23264621
28842250
details
UIMC1_HUMAN
FANCG_HUMAN
BioGRID
25132264
details
UIMC1_HUMAN
TRAIP_HUMAN
BioGRID
26781088
details
UIMC1_HUMAN
WBP2_HUMAN
BioGRID
27578003
details
UIMC1_HUMAN
UBP13_HUMAN
BioGRID
28569838
29396516
details
UIMC1_HUMAN
CBP_HUMAN
BioGRID
28680062
details
UIMC1_HUMAN
ZMYM3_HUMAN
BioGRID
28242625
details
UIMC1_HUMAN
UBB_HUMAN
BioGRID
24039796
details
UIMC1_HUMAN
CEP57_HUMAN
HPRD
12954732
details
UIMC1_HUMAN
RAD51_HUMAN
IntAct
17525340
details
UIMC1_HUMAN
H2AX_HUMAN
BioGRID, IntAct
18001824
29499138
31501894
details
UIMC1_HUMAN
BARD1_HUMAN
BioGRID, IntAct
17525341
19615732
details
UIMC1_HUMAN
TP53B_HUMAN
BioGRID, IntAct, UniProt
22884692
29656893
details
UIMC1_HUMAN
BLM_HUMAN
BioGRID, MINT
23708797
details
UIMC1_HUMAN
MDM2_HUMAN
BioGRID
19433585
details
UIMC1_HUMAN
H2B2E_HUMAN
BioGRID
19015238
details
UIMC1_HUMAN
SUMO1_HUMAN
BioGRID
23211528
details
UIMC1_HUMAN
PARP1_HUMAN
BioGRID
25252691
34079125
details
UIMC1_HUMAN
BRCA2_HUMAN
BioGRID
29499138
details
UIMC1_HUMAN
TNKS1_HUMAN
BioGRID
26845027
details
UIMC1_HUMAN
TNKS2_HUMAN
BioGRID
26845027
details
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