Entity Details

Primary name CK5P1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96SZ6
EntryNameCK5P1_HUMAN
FullNameMitochondrial tRNA methylthiotransferase CDK5RAP1
TaxID9606
Evidenceevidence at protein level
Length601
SequenceStatuscomplete
DateCreated2003-06-16
DateModified2021-06-02

Ontological Relatives

GenesCDK5RAP1

GO terms

Show/Hide Table
GOName
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0007420 brain development
GO:0019901 protein kinase binding
GO:0035597 N6-isopentenyladenosine methylthiotransferase activity
GO:0044877 protein-containing complex binding
GO:0045664 regulation of neuron differentiation
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045903 positive regulation of translational fidelity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0070131 positive regulation of mitochondrial translation
GO:0070900 mitochondrial tRNA modification

Subcellular Location

Show/Hide Table
Subcellular Location
Mitochondrion

Domains

Show/Hide Table
DomainNameCategoryType
IPR002792 TRAM domainDomainDomain
IPR005839 MethylthiotransferaseFamilyFamily
IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaBFamilyFamily
IPR006638 Elp3/MiaB/NifBDomainDomain
IPR007197 Radical SAMDomainDomain
IPR013848 Methylthiotransferase, N-terminalDomainDomain
IPR020612 Methylthiotransferase, conserved siteSiteConserved site
IPR023404 Radical SAM, alpha/beta horseshoeFamilyHomologous superfamily
IPR038135 Methylthiotransferase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions