Entity Details

Primary name FEV_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99581
EntryNameFEV_HUMAN
FullNameProtein FEV
TaxID9606
Evidenceevidence at protein level
Length238
SequenceStatuscomplete
DateCreated2008-07-22
DateModified2021-06-02

Ontological Relatives

GenesFEV

GO terms

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GOName
GO:0000785 chromatin
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010628 positive regulation of gene expression
GO:0016607 nuclear speck
GO:0030154 cell differentiation
GO:0042551 neuron maturation
GO:0048665 neuron fate specification
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000418 Ets domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
272120 OMIMSudden infant death syndrome (SIDS)SIDS is the sudden death of an infant younger than 1 year that remains unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of clinical history. Pathophysiologic mechanisms for SIDS may include respiratory dysfunction, cardiac dysrhythmias, cardiorespiratory instability, and inborn errors of metabolism, but definitive pathogenic mechanisms precipitating an infant sudden death remain elusive. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

0 interactions

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