Entity Details

Primary name ARPC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15144
EntryNameARPC2_HUMAN
FullNameActin-related protein 2/3 complex subunit 2
TaxID9606
Evidenceevidence at protein level
Length300
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesARPC2

GO terms

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GOName
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005885 Arp2/3 protein complex
GO:0005925 focal adhesion
GO:0010592 positive regulation of lamellipodium assembly
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030041 actin filament polymerization
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0035861 site of double-strand break
GO:0036195 muscle cell projection membrane
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043005 neuron projection
GO:0048013 ephrin receptor signaling pathway
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070358 actin polymerization-dependent cell motility
GO:0098978 glutamatergic synapse
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR007188 Actin-related protein 2/3 complex subunit 2FamilyFamily
IPR034666 Arp2/3 complex subunit 2/4FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08235 N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamideDrugbanksmall molecule
DB08236 (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-oneDrugbanksmall molecule