Entity Details

Primary name VAMP8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BV40
EntryNameVAMP8_HUMAN
FullNameVesicle-associated membrane protein 8
TaxID9606
Evidenceevidence at protein level
Length100
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesVAMP8

GO terms

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GOName
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005484 SNAP receptor activity
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006906 vesicle fusion
GO:0015031 protein transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016240 autophagosome membrane docking
GO:0019869 chloride channel inhibitor activity
GO:0019905 syntaxin binding
GO:0030667 secretory granule membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0030670 phagocytic vesicle membrane
GO:0031201 SNARE complex
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0031982 vesicle
GO:0035493 SNARE complex assembly
GO:0035577 azurophil granule membrane
GO:0035579 specific granule membrane
GO:0043312 neutrophil degranulation
GO:0046718 viral entry into host cell
GO:0048471 perinuclear region of cytoplasm
GO:0051607 defense response to virus
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070254 mucus secretion
GO:0070821 tertiary granule membrane
GO:0097352 autophagosome maturation
GO:0098594 mucin granule
GO:1903076 regulation of protein localization to plasma membrane
GO:1903531 negative regulation of secretion by cell
GO:1903595 positive regulation of histamine secretion by mast cell

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome membrane
Late endosome membrane
Lysosome membrane
Zymogen granule membrane

Domains

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DomainNameCategoryType
IPR001388 SynaptobrevinFamilyFamily
IPR016444 Synaptobrevin/Vesicle-associated membrane proteinFamilyFamily
IPR042855 v-SNARE, coiled-coil homology domainDomainDomain

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
VAMP8_HUMANMLH1_HUMANBioGRID, IntAct20706999 details
VAMP8_HUMANMPIP1_HUMANBioGRID, IntAct21988832 details
VAMP8_HUMANUB2G2_HUMANBioGRID, IntAct21988832 details
VAMP8_HUMANSNP23_HUMANBioGRID, HPRD10820264 12130530 12828989 details
VAMP8_HUMANSNAA_HUMANBioGRID, HPRD9614193 details
VAMP8_HUMANSTX1A_HUMANBioGRID, HPRD11112705 details
VAMP8_HUMANVAMP2_HUMANBioGRID, HPRD10336434 12130530 details
VAMP8_HUMANVAMP3_HUMANBioGRID12130530 details
VAMP8_HUMANPININ_HUMANIntAct16169070 details
VAMP8_HUMANSTX8_HUMANBioGRID, MINT11101518 19557002 details
VAMP8_HUMANSTX6_HUMANBioGRID, IntAct, MINT11839770 19557002 26186194 28514442 details
VAMP8_HUMANSTX7_HUMANBioGRID, HPRD, IntAct, MINT11101518 11278762 19557002 26186194 28514442 33422265 34079125 details
VAMP8_HUMANSTX17_HUMANBioGRID, DIP, IntAct23217709 25419848 31251111 33422265 details
VAMP8_HUMANSNP29_HUMANDIP, IntAct23217709 25419848 details
VAMP8_HUMANSNP47_HUMANIntAct26359495 details
VAMP8_HUMANSTX4_HUMANBioGRID, HPRD, IntAct10820264 12130530 29360461 details
VAMP8_HUMANSTX3_HUMANBioGRID, HPRD, IntAct10336434 26186194 26553929 28514442 29360461 details
VAMP8_HUMANSTX11_HUMANBioGRID, IntAct25748427 28514442 details
VAMP8_HUMANSTX2_HUMANBioGRID12828989 29360461 details
VAMP8_HUMANVTI1A_HUMANBioGRID11101518 details
VAMP8_HUMANVATB1_HUMANBioGRID21674799 details
VAMP8_HUMAN1433E_HUMANBioGRID17979178 details
VAMP8_HUMANATP4A_HUMANBioGRID17255364 details
VAMP8_HUMANUBP8_HUMANBioGRID18388320 details
VAMP8_HUMANSTABP_HUMANBioGRID18388320 details
VAMP8_HUMANMLP3B_HUMANBioGRID27791468 details
VAMP8_HUMANBAKOR_HUMANBioGRID30584088 details
VAMP8_HUMANTRIM6_HUMANBioGRID31694946 details
VAMP8_HUMANSNP25_HUMANHPRD10336434 details
VAMP8_HUMANSTX1B_HUMANHPRD11112705 details