Entity Details

Primary name OSBL8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZF1
EntryNameOSBL8_HUMAN
FullNameOxysterol-binding protein-related protein 8
TaxID9606
Evidenceevidence at protein level
Length889
SequenceStatuscomplete
DateCreated2002-02-11
DateModified2021-06-02

Ontological Relatives

GenesOSBPL8

GO terms

Show/Hide Table
GOName
GO:0001786 phosphatidylserine binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0010891 negative regulation of sequestering of triglyceride
GO:0015248 sterol transporter activity
GO:0015485 cholesterol binding
GO:0015914 phospholipid transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030336 negative regulation of cell migration
GO:0031965 nuclear membrane
GO:0032148 activation of protein kinase B activity
GO:0032541 cortical endoplasmic reticulum
GO:0032934 sterol binding
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0043231 intracellular membrane-bounded organelle
GO:0045444 fat cell differentiation
GO:0046326 positive regulation of glucose import
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0051897 positive regulation of protein kinase B signaling
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0090204 protein localization to nuclear pore
GO:0140343 phosphatidylserine transfer activity

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane
Nucleus membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000648 Oxysterol-binding proteinFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR018494 Oxysterol-binding protein, conserved siteSiteConserved site
IPR037239 Oxysterol-binding protein superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table