Entity Details
| Primary name |
IRX2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9BZI1 |
| EntryName | IRX2_HUMAN |
| FullName | Iroquois-class homeodomain protein IRX-2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 471 |
| SequenceStatus | complete |
| DateCreated | 2002-04-16 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0000785 | chromatin |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0005634 | nucleus |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0030182 | neuron differentiation |
| GO:0043565 | sequence-specific DNA binding |
| GO:0048468 | cell development |
| GO:0072086 | specification of loop of Henle identity |
| GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development |
Subcellular Location
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| Subcellular Location |
| Nucleus |
Domains
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| Domain | Name | Category | Type |
| IPR001356 | Homeobox domain | Domain | Domain |
| IPR003893 | Iroquois-class homeodomain protein | Domain | Domain |
| IPR008422 | Homeobox KN domain | Domain | Domain |
| IPR009057 | Homeobox-like domain superfamily | Family | Homologous superfamily |
| IPR017970 | Homeobox, conserved site | Site | Conserved site |
Interactions
3 interactions