Entity Details

Primary name BC11A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H165
EntryNameBC11A_HUMAN
FullNameB-cell lymphoma/leukemia 11A
TaxID9606
Evidenceevidence at protein level
Length835
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesBCL11A

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001067 transcription regulatory region nucleic acid binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010628 positive regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0010977 negative regulation of neuron projection development
GO:0014069 postsynaptic density
GO:0016925 protein sumoylation
GO:0019901 protein kinase binding
GO:0030517 negative regulation of axon extension
GO:0032463 negative regulation of protein homooligomerization
GO:0042803 protein homodimerization activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0048671 negative regulation of collateral sprouting
GO:0048672 positive regulation of collateral sprouting
GO:0050773 regulation of dendrite development
GO:1903860 negative regulation of dendrite extension
GO:1904800 negative regulation of neuron remodeling
GO:1905232 cellular response to L-glutamate
GO:2000171 negative regulation of dendrite development
GO:2000173 negative regulation of branching morphogenesis of a nerve

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
617101 OMIMIntellectual developmental disorder with persistence of fetal hemoglobin (IDPFH)An autosomal dominant disorder characterized by delayed psychomotor development, intellectual disability, variable dysmorphic features, including microcephaly, downslanting palpebral fissures, strabismus, and external ear abnormalities, and asymptomatic persistence of fetal hemoglobin. The disease is caused by variants affecting the gene represented in this entry.

Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
BC11A_HUMANBCL6_HUMANBioGRID, IntAct16147992 16704730 details
BC11A_HUMANYMEL1_HUMANBioGRID, IntAct21988832 details
BC11A_HUMANCDCA3_HUMANBioGRID, IntAct21988832 details
BC11A_HUMANACTC_HUMANBioGRID, IntAct21988832 details
BC11A_HUMANCDK4_HUMANBioGRID, IntAct22094256 details
BC11A_HUMANCDK6_HUMANBioGRID, IntAct22094256 details
BC11A_HUMANHDAC1_HUMANBioGRID, IntAct16091750 23752268 28514442 29263092 details
BC11A_HUMANHDAC2_HUMANBioGRID, IntAct23752268 24981860 29263092 details
BC11A_HUMANRBBP4_HUMANBioGRID, IntAct, MINT24981860 27705803 29263092 details
BC11A_HUMANRBBP7_HUMANBioGRID, IntAct26186194 27705803 28514442 29263092 details
BC11A_HUMANZBT24_HUMANBioGRID, IntAct25416956 details
BC11A_HUMANNCK2_HUMANBioGRID, IntAct25416956 32296183 details
BC11A_HUMANRBTN1_HUMANBioGRID, IntAct25416956 details
BC11A_HUMANGMCL2_HUMANIntAct25416956 details
BC11A_HUMANNFAM1_HUMANBioGRID, IntAct32296183 details
BC11A_HUMANPIN1_HUMANBioGRID, IntAct32296183 details
BC11A_HUMANMO4L2_HUMANBioGRID, IntAct32296183 details
BC11A_HUMANMTA1_HUMANBioGRID, IntAct16091750 24981860 26186194 28514442 29263092 details
BC11A_HUMANCOT1_HUMANBioGRID, HPRD10744719 23975195 details
BC11A_HUMANSIR1_HUMANBioGRID15639232 details
BC11A_HUMANBC11A_HUMANBioGRID12196208 16704730 details
BC11A_HUMANA4_HUMANBioGRID21832049 details
BC11A_HUMANCOT2_HUMANBioGRID, HPRD10744719 23975195 details
BC11A_HUMANNR2E1_HUMANBioGRID22675500 23975195 details
BC11A_HUMANNR2E3_HUMANBioGRID23975195 details
BC11A_HUMANNR2F6_HUMANBioGRID23975195 details
BC11A_HUMANUBC9_HUMANBioGRID18681895 details
BC11A_HUMANEZH2_HUMANBioGRID24981860 29263092 details
BC11A_HUMANSUZ12_HUMANBioGRID24981860 29263092 details
BC11A_HUMANSIN3A_HUMANBioGRID24981860 29263092 details
BC11A_HUMANMTA2_HUMANBioGRID, DIP16091750 24981860 26816381 details
BC11A_HUMANFXR2_HUMANMINT21653829 details
BC11A_HUMANTSC1_HUMANMINT21653829 details
BC11A_HUMANCHD4_HUMANBioGRID16091750 24981860 28977666 details
BC11A_HUMANMBD3_HUMANBioGRID16091750 24981860 details
BC11A_HUMANPIAS3_HUMANBioGRID18681895 details
BC11A_HUMANSPT5H_HUMANBioGRID29395067 details