Entity Details

Primary name E41L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H4G0
EntryNameE41L1_HUMAN
FullNameBand 4.1-like protein 1
TaxID9606
Evidenceevidence at protein level
Length881
SequenceStatuscomplete
DateCreated2001-07-11
DateModified2021-06-02

Ontological Relatives

GenesEPB41L1

GO terms

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GOName
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0030866 cortical actin cytoskeleton organization
GO:0031032 actomyosin structure organization

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR000798 Ezrin/radixin/moesin-likeFamilyFamily
IPR007477 SAB domainDomainDomain
IPR008379 Band 4.1, C-terminalDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014847 FERM adjacent (FA)DomainDomain
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
614257 OMIMMental retardation, autosomal dominant 11 (MRD11)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. The disease is caused by variants affecting the gene represented in this entry.