Entity Details

Primary name NANOG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H9S0
EntryNameNANOG_HUMAN
FullNameHomeobox protein NANOG
TaxID9606
Evidenceevidence at protein level
Length305
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesNANOG

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001714 endodermal cell fate specification
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010468 regulation of gene expression
GO:0019221 cytokine-mediated signaling pathway
GO:0019827 stem cell population maintenance
GO:0030154 cell differentiation
GO:0035019 somatic stem cell population maintenance
GO:0043231 intracellular membrane-bounded organelle
GO:0045595 regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000648 positive regulation of stem cell proliferation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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