Entity Details

Primary name PRD16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HAZ2
EntryNamePRD16_HUMAN
FullNameHistone-lysine N-methyltransferase PRDM16
TaxID9606
Evidenceevidence at protein level
Length1276
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesPRDM16

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0016235 aggresome
GO:0017053 transcription repressor complex
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030853 negative regulation of granulocyte differentiation
GO:0043457 regulation of cellular respiration
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0050873 brown fat cell differentiation
GO:0070828 heterochromatin organization
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily
IPR044410 PRDM16, PR/SET domainDomainDomain

Diseases

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