Entity Details

Primary name SETD4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NVD3
EntryNameSETD4_HUMAN
FullNameSET domain-containing protein 4
TaxID9606
Evidenceevidence at protein level
Length440
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesSETD4

GO terms

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GOName
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018023 peptidyl-lysine trimethylation
GO:0018026 peptidyl-lysine monomethylation
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034773 histone H4-K20 trimethylation
GO:0042799 histone methyltransferase activity (H4-K20 specific)
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0044648 histone H3-K4 dimethylation
GO:0050729 positive regulation of inflammatory response
GO:0071863 regulation of cell proliferation in bone marrow
GO:0097692 histone H3-K4 monomethylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR015353 Rubisco LSMT, substrate-binding domainDomainDomain
IPR016852 SET domain methyltransferaseFamilyFamily
IPR036464 Rubisco LSMT, substrate-binding domain superfamilyFamilyHomologous superfamily
IPR044429 SETD4, SET domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SETD4_HUMANCIA2A_HUMANBioGRID, IntAct32296183 details