Entity Details

Primary name FGF16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43320
EntryNameFGF16_HUMAN
FullNameFibroblast growth factor 16
TaxID9606
Evidenceevidence at protein level
Length207
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesFGF16

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009266 response to temperature stimulus
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0051897 positive regulation of protein kinase B signaling
GO:0070349 positive regulation of brown fat cell proliferation
GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028285 Fibroblast growth factor 16FamilyFamily

Diseases

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Disease IDSourceNameDescription
309630 OMIMMetacarpal 4-5 fusion (MF4)A rare congenital malformation of the hand characterized by the partial or complete fusion of the fourth and fifth metacarpals. The anomaly occurs as an isolated trait or part of a syndrome. The disease is caused by variants affecting the gene represented in this entry.