Entity Details

Primary name RASL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43374
EntryNameRASL2_HUMAN
FullNameRas GTPase-activating protein 4
TaxID9606
Evidenceevidence at transcript level
Length803
SequenceStatuscomplete
DateCreated2001-05-04
DateModified2021-06-02

Ontological Relatives

GenesRASA4

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0005096 GTPase activator activity
GO:0005543 phospholipid binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0034260 negative regulation of GTPase activity
GO:0046580 negative regulation of Ras protein signal transduction
GO:0046872 metal ion binding
GO:0071277 cellular response to calcium ion

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001562 Zinc finger, Btk motifSiteConserved site
IPR001849 Pleckstrin homology domainDomainDomain
IPR001936 Ras GTPase-activating domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR023152 Ras GTPase-activating protein, conserved siteSiteConserved site
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037777 RASA4, PH domainDomainDomain
IPR039360 Ras GTPase-activating proteinFamilyFamily

Diseases

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