Entity Details

Primary name C1RL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZP8
EntryNameC1RL_HUMAN
FullNameComplement C1r subcomponent-like protein
TaxID9606
Evidenceevidence at protein level
Length487
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesC1RL

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005615 extracellular space
GO:0006958 complement activation, classical pathway
GO:0031638 zymogen activation
GO:0045087 innate immune response
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000859 CUB domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
C1RL_HUMANOSTP_HUMANBioGRID22779921 details
C1RL_HUMANHPT_HUMANHPRD15385675 details