Entity Details

Primary name PDP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9P0J1
EntryNamePDP1_HUMAN
FullName[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length537
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesPDP1

GO terms

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GOName
GO:0004722 protein serine/threonine phosphatase activity
GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006470 protein dephosphorylation
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0035970 peptidyl-threonine dephosphorylation
GO:0046872 metal ion binding
GO:1904184 positive regulation of pyruvate dehydrogenase activity

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR000222 PPM-type phosphatase, divalent cation bindingSiteBinding site
IPR001932 PPM-type phosphatase domainDomainDomain
IPR015655 Protein phosphatase 2C familyFamilyFamily
IPR036457 PPM-type phosphatase domain superfamilyFamilyHomologous superfamily

Diseases

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