Entity Details

Primary name GHRL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBU3
EntryNameGHRL_HUMAN
FullNameAppetite-regulating hormone
TaxID9606
Evidenceevidence at protein level
Length117
SequenceStatuscomplete
DateCreated2001-12-13
DateModified2021-06-02

Ontological Relatives

GenesGHRL

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001664 G protein-coupled receptor binding
GO:0001696 gastric acid secretion
GO:0001937 negative regulation of endothelial cell proliferation
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0006006 glucose metabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008154 actin polymerization or depolymerization
GO:0008343 adult feeding behavior
GO:0009725 response to hormone
GO:0009755 hormone-mediated signaling pathway
GO:0016358 dendrite development
GO:0016525 negative regulation of angiogenesis
GO:0016608 growth hormone-releasing hormone activity
GO:0030252 growth hormone secretion
GO:0030296 protein tyrosine kinase activator activity
GO:0030424 axon
GO:0031768 ghrelin receptor binding
GO:0032024 positive regulation of insulin secretion
GO:0032095 regulation of response to food
GO:0032100 positive regulation of appetite
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0034774 secretory granule lumen
GO:0035483 gastric emptying
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0040010 positive regulation of growth rate
GO:0040013 negative regulation of locomotion
GO:0040018 positive regulation of multicellular organism growth
GO:0042127 regulation of cell population proliferation
GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep
GO:0043066 negative regulation of apoptotic process
GO:0043400 cortisol secretion
GO:0043627 response to estrogen
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676 negative regulation of insulin secretion
GO:0046697 decidualization
GO:0050728 negative regulation of inflammatory response
GO:0051216 cartilage development
GO:0051461 positive regulation of corticotropin secretion
GO:0051464 positive regulation of cortisol secretion
GO:0051602 response to electrical stimulus
GO:0051965 positive regulation of synapse assembly
GO:0051969 regulation of transmission of nerve impulse
GO:0060079 excitatory postsynaptic potential
GO:0060124 positive regulation of growth hormone secretion
GO:0060399 positive regulation of growth hormone receptor signaling pathway
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099170 postsynaptic modulation of chemical synaptic transmission
GO:0099175 regulation of postsynapse organization
GO:0120058 positive regulation of small intestinal transit
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1903012 positive regulation of bone development
GO:1903672 positive regulation of sprouting angiogenesis
GO:1904000 positive regulation of eating behavior
GO:1904179 positive regulation of adipose tissue development
GO:1904346 positive regulation of gastric mucosal blood circulation
GO:1904349 positive regulation of small intestine smooth muscle contraction
GO:1905333 regulation of gastric motility
GO:1905564 positive regulation of vascular endothelial cell proliferation

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR005441 Preproghrelin peptideFamilyFamily
IPR006737 Motilin/ghrelin-associated peptideDomainDomain
IPR006738 Motilin/ghrelinDomainDomain

Diseases

Show/Hide Table