Entity Details

Primary name HACL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJ83
EntryNameHACL1_HUMAN
FullName2-hydroxyacyl-CoA lyase 1
TaxID9606
Evidenceevidence at protein level
Length578
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesHACL1

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001561 fatty acid alpha-oxidation
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006625 protein targeting to peroxisome
GO:0006631 fatty acid metabolic process
GO:0008104 protein localization
GO:0016830 carbon-carbon lyase activity
GO:0030976 thiamine pyrophosphate binding
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0097089 methyl-branched fatty acid metabolic process
GO:1903512 phytanic acid metabolic process

Subcellular Location

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Subcellular Location
Peroxisome

Domains

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DomainNameCategoryType
IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-bindingDomainDomain
IPR012000 Thiamine pyrophosphate enzyme, central domainDomainDomain
IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domainDomainDomain
IPR029035 DHS-like NAD/FAD-binding domain superfamilyFamilyHomologous superfamily
IPR029061 Thiamin diphosphate-binding foldFamilyHomologous superfamily

Diseases

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Interactions

5 interactions