Entity Details

Primary name CPSF3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKF6
EntryNameCPSF3_HUMAN
FullNameCleavage and polyadenylation specificity factor subunit 3
TaxID9606
Evidenceevidence at protein level
Length684
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesCPSF3

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0004521 endoribonuclease activity
GO:0005654 nucleoplasm
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
GO:0006369 termination of RNA polymerase II transcription
GO:0006378 mRNA polyadenylation
GO:0006379 mRNA cleavage
GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage
GO:0006406 mRNA export from nucleus
GO:0008409 5'-3' exonuclease activity
GO:0031124 mRNA 3'-end processing
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001279 Metallo-beta-lactamaseDomainDomain
IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domainDomainDomain
IPR021718 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-termDomainDomain
IPR022712 Beta-Casp domainDomainDomain
IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-likeFamilyHomologous superfamily

Diseases

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