Entity Details

Primary name MYT1L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UL68
EntryNameMYT1L_HUMAN
FullNameMyelin transcription factor 1-like protein
TaxID9606
Evidenceevidence at transcript level
Length1186
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesMYT1L

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008270 zinc ion binding
GO:0030182 neuron differentiation
GO:0048663 neuron fate commitment
GO:0048665 neuron fate specification
GO:0048666 neuron development

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR002515 Zinc finger, C2H2C-typeRepeatRepeat
IPR013681 Myelin transcription factor 1DomainDomain
IPR036060 Zinc finger, C2H2C-type superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
616521 OMIMMental retardation, autosomal dominant 39 (MRD39)A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRD39 patients show delayed psychomotor development and autistic features. The disease is caused by variants affecting the gene represented in this entry.