Entity Details

Primary name CNOT6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULM6
EntryNameCNOT6_HUMAN
FullNameCCR4-NOT transcription complex subunit 6
TaxID9606
Evidenceevidence at protein level
Length557
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0003723 RNA binding
GO:0004532 exoribonuclease activity
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006417 regulation of translation
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008284 positive regulation of cell population proliferation
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0016020 membrane
GO:0030014 CCR4-NOT complex
GO:0030374 nuclear receptor coactivator activity
GO:0035195 gene silencing by miRNA
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0046872 metal ion binding
GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR034966 CCR4-NOT transcription complex subunit 6DomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily

Diseases

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