Entity Details
| Primary name |
DLEC1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9Y238 |
| EntryName | DLEC1_HUMAN |
| FullName | Deleted in lung and esophageal cancer protein 1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 1755 |
| SequenceStatus | complete |
| DateCreated | 2005-10-25 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Cytoplasm |
Domains
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| Domain | Name | Category | Type |
| IPR013783 | Immunoglobulin-like fold | Family | Homologous superfamily |
| IPR033304 | Deleted in lung and esophageal cancer protein 1 | Family | Family |
Diseases
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| Disease ID | Source | Name | Description |
| 211980 | OMIM | Lung cancer (LNCR) | A common malignancy affecting tissues of the lung. The most common form of lung cancer is non-small cell lung cancer (NSCLC) that can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. NSCLC is often diagnosed at an advanced stage and has a poor prognosis. The gene represented in this entry may be involved in disease pathogenesis. DLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of lung cancer. |
| 133239 | OMIM | Esophageal cancer (ESCR) | A malignancy of the esophagus. The most common types are esophageal squamous cell carcinoma and adenocarcinoma. Cancer of the esophagus remains a devastating disease because it is usually not detected until it has progressed to an advanced incurable stage. The gene represented in this entry may be involved in disease pathogenesis. DLEC1 silencing due to promoter methylation and aberrant transcription may be implicated in the development of esophageal cancer. |
Interactions
0 interactions
| Interactor | Partner | Sources | Publications | Link |