Entity Details
| Primary name |
SC6A5_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9Y345 |
| EntryName | SC6A5_HUMAN |
| FullName | Sodium- and chloride-dependent glycine transporter 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 797 |
| SequenceStatus | complete |
| DateCreated | 2001-09-26 |
| DateModified | 2021-06-02 |
Subcellular Location
Show/Hide Table
| Subcellular Location |
| Cell membrane |
Domains
Show/Hide Table
| Domain | Name | Category | Type |
| IPR000175 | Sodium:neurotransmitter symporter | Family | Family |
| IPR037272 | Sodium:neurotransmitter symporter superfamily | Family | Homologous superfamily |
Diseases
Show/Hide Table
| Disease ID | Source | Name | Description |
| 614618 | OMIM | Hyperekplexia 3 (HKPX3) | A neurologic disorder characterized by neonatal hypertonia, an exaggerated startle response to tactile or acoustic stimuli, and life-threatening neonatal apnea episodes. Notably, in some cases, symptoms resolved in the first year of life. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
Show/Hide Table
| Drug | Name | Source | Type |
| DB00145 | Glycine | Drugbank | small molecule |
Interactions
3 interactions