Entity Details

Primary name TIM16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y3D7
EntryNameTIM16_HUMAN
FullNameMitochondrial import inner membrane translocase subunit TIM16
TaxID9606
Evidenceevidence at protein level
Length125
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPAM16

GO terms

Show/Hide Table
GOName
GO:0001405 PAM complex, Tim23 associated import motor
GO:0001503 ossification
GO:0005744 TIM23 mitochondrial import inner membrane translocase complex
GO:0005759 mitochondrial matrix
GO:0030150 protein import into mitochondrial matrix
GO:0031314 extrinsic component of mitochondrial inner membrane
GO:0032780 negative regulation of ATPase activity
GO:0032991 protein-containing complex

Subcellular Location

Show/Hide Table
Subcellular Location
Mitochondrion inner membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR005341 Mitochondrial import inner membrane translocase subunit Tim16FamilyFamily
IPR036869 Chaperone J-domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
613320 OMIMSpondylometaphyseal dysplasia, Megarbane-Dagher-Melike type (SMDMDM)An autosomal recessive disease characterized by pre- and postnatal short stature, developmental delay, dysmorphic facial appearance, narrow chest, prominent abdomen, platyspondyly, and short limbs. The disease is caused by variants affecting the gene represented in this entry.