Entity Details

Primary name CERT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5P4
EntryNameCERT_HUMAN
FullNameCeramide transfer protein
TaxID9606
Evidenceevidence at protein level
Length624
SequenceStatuscomplete
DateCreated2002-05-15
DateModified2021-06-02

Ontological Relatives

GenesCERT1

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006672 ceramide metabolic process
GO:0006936 muscle contraction
GO:0006955 immune response
GO:0007029 endoplasmic reticulum organization
GO:0007165 signal transduction
GO:0008283 cell population proliferation
GO:0016020 membrane
GO:0016301 kinase activity
GO:0030148 sphingolipid biosynthetic process
GO:0034976 response to endoplasmic reticulum stress
GO:0035621 ER to Golgi ceramide transport
GO:0035627 ceramide transport
GO:0042802 identical protein binding
GO:0055088 lipid homeostasis
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070584 mitochondrion morphogenesis
GO:0097001 ceramide binding
GO:0120009 intermembrane lipid transfer
GO:0120012 intermembrane sphingolipid transfer
GO:0120017 ceramide transfer activity
GO:1902387 ceramide 1-phosphate binding
GO:1902388 ceramide 1-phosphate transfer activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR002913 START domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR023393 START-like domain superfamilyFamilyHomologous superfamily
IPR041952 STARD11, START domainDomainDomain

Diseases

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Disease IDSourceNameDescription
616351 OMIMMental retardation, autosomal dominant 34 (MRD34)A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. The disease is caused by variants affecting the gene represented in this entry.