Entity Details

Primary name MRCKB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5S2
EntryNameMRCKB_HUMAN
FullNameSerine/threonine-protein kinase MRCK beta
TaxID9606
Evidenceevidence at protein level
Length1711
SequenceStatuscomplete
DateCreated2005-11-08
DateModified2021-06-02

Ontological Relatives

GenesCDC42BPB

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0007010 cytoskeleton organization
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0016477 cell migration
GO:0018107 peptidyl-threonine phosphorylation
GO:0030027 lamellipodium
GO:0031032 actomyosin structure organization
GO:0031252 cell leading edge
GO:0031267 small GTPase binding
GO:0031532 actin cytoskeleton reorganization
GO:0035556 intracellular signal transduction
GO:0042641 actomyosin
GO:0044877 protein-containing complex binding
GO:0070062 extracellular exosome
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000095 CRIB domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR001180 Citron homology (CNH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014930 Myotonic dystrophy protein kinase, coiled coilDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR031597 KELK-motif containing domainDomainDomain
IPR033232 Serine/threonine-protein kinase MRCK betaFamilyFamily
IPR042718 Serine/threonine-protein kinase MRCK beta, catalytic domainDomainDomain

Diseases

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