Entity Details

Primary name FCG3B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75015
EntryNameFCG3B_HUMAN
FullNameLow affinity immunoglobulin gamma Fc region receptor III-B
TaxID9606
Evidenceevidence at protein level
Length233
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFCGR3B

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0019864 IgG binding
GO:0030667 secretory granule membrane
GO:0031225 anchored component of membrane
GO:0043312 neutrophil degranulation
GO:0050776 regulation of immune response
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00002 CetuximabDrugbankbiotech
DB00005 EtanerceptDrugbankbiotech
DB00028 Human immunoglobulin GDrugbankbiotech
DB00056 Gemtuzumab ozogamicinDrugbankbiotech
DB00075 MuromonabDrugbankbiotech
DB00087 AlemtuzumabDrugbankbiotech
DB00092 AlefaceptDrugbankbiotech
DB00108 NatalizumabDrugbankbiotech
DB00110 PalivizumabDrugbankbiotech
DB00111 DaclizumabDrugbankbiotech
DB06607 CatumaxomabDrugbankbiotech
DB11767 SarilumabDrugbankbiotech

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
FCG3B_HUMANSAMP_HUMANBioGRID, HPRD11359830 details