Entity Details

Primary name CAC1H_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95180
EntryNameCAC1H_HUMAN
FullNameVoltage-dependent T-type calcium channel subunit alpha-1H
TaxID9606
Evidenceevidence at protein level
Length2353
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCACNA1H

GO terms

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GOName
GO:0001518 voltage-gated sodium channel complex
GO:0005244 voltage-gated ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005887 integral component of plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006936 muscle contraction
GO:0007517 muscle organ development
GO:0007520 myoblast fusion
GO:0008016 regulation of heart contraction
GO:0008332 low voltage-gated calcium channel activity
GO:0016021 integral component of membrane
GO:0019228 neuronal action potential
GO:0032342 aldosterone biosynthetic process
GO:0032870 cellular response to hormone stimulus
GO:0034651 cortisol biosynthetic process
GO:0034765 regulation of ion transmembrane transport
GO:0035865 cellular response to potassium ion
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046872 metal ion binding
GO:0070509 calcium ion import
GO:0086010 membrane depolarization during action potential
GO:0097110 scaffold protein binding
GO:0098662 inorganic cation transmembrane transport
GO:2000344 positive regulation of acrosome reaction

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR005445 Voltage-dependent calcium channel, T-type, alpha-1 subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00270 IsradipineDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00568 CinnarizineDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB01023 FelodipineDrugbanksmall molecule
DB01054 NitrendipineDrugbanksmall molecule
DB01115 NifedipineDrugbanksmall molecule
DB01244 BepridilDrugbanksmall molecule
DB01388 MibefradilDrugbanksmall molecule
DB04841 FlunarizineDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB09089 TrimebutineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09238 ManidipineDrugbanksmall molecule
DB11093 Calcium citrateDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule