Entity Details
| Primary name |
KAD1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P00568 |
| EntryName | KAD1_HUMAN |
| FullName | Adenylate kinase isoenzyme 1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 194 |
| SequenceStatus | complete |
| DateCreated | 1986-07-21 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Cytoplasm |
Domains
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| Domain | Name | Category | Type |
| IPR000850 | Adenylate kinase/UMP-CMP kinase | Family | Family |
| IPR006267 | Adenylate kinase, isozyme 1/5 | Family | Family |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Family | Homologous superfamily |
| IPR028582 | Adenylate kinase isoenzyme 1 | Family | Family |
| IPR033690 | Adenylate kinase, conserved site | Site | Conserved site |
Diseases
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| Disease ID | Source | Name | Description |
| 612631 | OMIM | Hemolytic anemia due to adenylate kinase deficiency (HAAKD) | A disease characterized by hemolytic anemia and undetectable erythrocyte adenylate kinase activity. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB01717 | Bis(Adenosine)-5'-Pentaphosphate | Drugbank | small molecule |
| DB09299 | Tenofovir alafenamide | Drugbank | small molecule |
| DB14126 | Tenofovir | Drugbank | small molecule |
Interactions
7 interactions