Entity Details

Primary name A1AG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02763
EntryNameA1AG1_HUMAN
FullNameAlpha-1-acid glycoprotein 1
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesORM1

GO terms

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GOName
GO:0002576 platelet degranulation
GO:0002682 regulation of immune system process
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006953 acute-phase response
GO:0006954 inflammatory response
GO:0031093 platelet alpha granule lumen
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032732 positive regulation of interleukin-1 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:1904724 tertiary granule lumen

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000566 Lipocalin/cytosolic fatty-acid binding domainDomainDomain
IPR001500 Alpha-1-acid glycoproteinFamilyFamily
IPR012674 CalycinFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00243 RanolazineDrugbanksmall molecule
DB00246 ZiprasidoneDrugbanksmall molecule
DB00276 AmsacrineDrugbanksmall molecule
DB00278 ArgatrobanDrugbanksmall molecule
DB00280 DisopyramideDrugbanksmall molecule
DB00281 LidocaineDrugbanksmall molecule
DB00289 AtomoxetineDrugbanksmall molecule
DB00317 GefitinibDrugbanksmall molecule
DB00321 AmitriptylineDrugbanksmall molecule
DB00332 IpratropiumDrugbanksmall molecule
DB00333 MethadoneDrugbanksmall molecule
DB00334 OlanzapineDrugbanksmall molecule
DB00343 DiltiazemDrugbanksmall molecule
DB00396 ProgesteroneDrugbanksmall molecule
DB00404 AlprazolamDrugbanksmall molecule
DB00409 RemoxiprideDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00454 MeperidineDrugbanksmall molecule
DB00457 PrazosinDrugbanksmall molecule
DB00458 ImipramineDrugbanksmall molecule
DB00472 FluoxetineDrugbanksmall molecule
DB00476 DuloxetineDrugbanksmall molecule
DB00477 ChlorpromazineDrugbanksmall molecule
DB00481 RaloxifeneDrugbanksmall molecule
DB00490 BuspironeDrugbanksmall molecule
DB00497 OxycodoneDrugbanksmall molecule
DB00503 RitonavirDrugbanksmall molecule
DB00512 VancomycinSwissprotsmall molecule
DB00530 ErlotinibDrugbanksmall molecule
DB00540 NortriptylineDrugbanksmall molecule
DB00543 AmoxapineDrugbanksmall molecule
DB00571 PropranololDrugbanksmall molecule
DB00598 LabetalolDrugbanksmall molecule
DB00608 ChloroquineDrugbanksmall molecule
DB00619 ImatinibDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00682 WarfarinDrugbanksmall molecule
DB00706 TamsulosinDrugbanksmall molecule
DB00731 NateglinideDrugbanksmall molecule
DB00734 RisperidoneDrugbanksmall molecule
DB00802 AlfentanilDrugbanksmall molecule
DB00808 IndapamideDrugbanksmall molecule
DB00813 FentanylDrugbanksmall molecule
DB00857 TerbinafineDrugbanksmall molecule
DB00864 TacrolimusDrugbanksmall molecule
DB00907 CocaineDrugbanksmall molecule
DB00908 QuinidineDrugbanksmall molecule
DB00934 MaprotilineDrugbanksmall molecule
DB00938 SalmeterolDrugbanksmall molecule
DB00946 PhenprocoumonDrugbanksmall molecule
DB00950 FexofenadineDrugbanksmall molecule
DB00975 DipyridamoleDrugbanksmall molecule
DB01029 IrbesartanDrugbanksmall molecule
DB01041 ThalidomideDrugbanksmall molecule
DB01045 RifampicinDrugbanksmall molecule
DB01062 OxybutyninDrugbanksmall molecule
DB01072 AtazanavirDrugbanksmall molecule
DB01115 NifedipineDrugbanksmall molecule
DB01126 DutasterideDrugbanksmall molecule
DB01142 DoxepinDrugbanksmall molecule
DB01151 DesipramineDrugbanksmall molecule
DB01156 BupropionDrugbanksmall molecule
DB01190 ClindamycinDrugbanksmall molecule
DB01195 FlecainideDrugbanksmall molecule
DB01203 NadololDrugbanksmall molecule
DB01232 SaquinavirDrugbanksmall molecule
DB01233 MetoclopramideDrugbanksmall molecule
DB01264 DarunavirDrugbanksmall molecule
DB01359 PenbutololDrugbanksmall molecule
DB01418 AcenocoumarolDrugbanksmall molecule
DB01426 AjmalineDrugbanksmall molecule
DB01429 AprindineDrugbanksmall molecule
DB01591 SolifenacinDrugbanksmall molecule
DB01601 LopinavirDrugbanksmall molecule
DB01611 HydroxychloroquineDrugbanksmall molecule
DB01685 TopiroxostatDrugbanksmall molecule
DB04821 NomifensineDrugbanksmall molecule
DB05294 VandetanibDrugbanksmall molecule
DB05521 TelaprevirDrugbanksmall molecule
DB05812 AbirateroneDrugbanksmall molecule
DB06216 AsenapineDrugbanksmall molecule
DB08820 IvacaftorDrugbanksmall molecule
DB08828 VismodegibDrugbanksmall molecule
DB08860 PitavastatinDrugbanksmall molecule
DB08867 UlipristalDrugbanksmall molecule
DB08881 VemurafenibDrugbanksmall molecule
DB08893 MirabegronDrugbanksmall molecule
DB08907 CanagliflozinDrugbanksmall molecule
DB08931 RiociguatDrugbanksmall molecule
DB09053 IbrutinibDrugbanksmall molecule
DB09204 ArotinololDrugbanksmall molecule
DB09229 AranidipineDrugbanksmall molecule
DB09236 LacidipineDrugbanksmall molecule
DB09262 ImidafenacinDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11575 GrazoprevirDrugbanksmall molecule
DB11637 DelamanidSwissprotsmall molecule
DB11641 VinflunineDrugbanksmall molecule
DB11642 PitolisantDrugbanksmall molecule
DB11689 SelumetinibDrugbanksmall molecule
DB11703 AcalabrutinibDrugbanksmall molecule
DB11757 IstradefyllineDrugbanksmall molecule
DB11828 NeratinibDrugbanksmall molecule
DB11853 RelugolixDrugbanksmall molecule
DB12001 AbemaciclibDrugbanksmall molecule
DB12466 FavipiravirDrugbanksmall molecule
DB12674 LurbinectedinSwissprotsmall molecule
DB12978 PexidartinibDrugbanksmall molecule
DB14582 PatisiranSwissprotbiotech
DB14840 RipretinibDrugbanksmall molecule