Entity Details

Primary name CCKN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06307
EntryNameCCKN_HUMAN
FullNameCholecystokinin
TaxID9606
Evidenceevidence at protein level
Length115
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesCCK

GO terms

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GOName
GO:0001764 neuron migration
GO:0001836 release of cytochrome c from mitochondria
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007409 axonogenesis
GO:0007586 digestion
GO:0007613 memory
GO:0008284 positive regulation of cell population proliferation
GO:0008542 visual learning
GO:0014049 positive regulation of glutamate secretion
GO:0030424 axon
GO:0030425 dendrite
GO:0031334 positive regulation of protein-containing complex assembly
GO:0032099 negative regulation of appetite
GO:0042755 eating behavior
GO:0043065 positive regulation of apoptotic process
GO:0043194 axon initial segment
GO:0043195 terminal bouton
GO:0043203 axon hillock
GO:0043204 perikaryon
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051428 peptide hormone receptor binding
GO:0051901 positive regulation of mitochondrial depolarization
GO:1903999 negative regulation of eating behavior
GO:1904058 positive regulation of sensory perception of pain
GO:2000986 negative regulation of behavioral fear response
GO:2000987 positive regulation of behavioral fear response

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001651 Gastrin/cholecystokinin peptide hormoneDomainDomain
IPR013152 Gastrin/cholecystokinin, conserved siteSiteConserved site
IPR015499 Cholecystokinin-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB13729 CamostatDrugbanksmall molecule

Interactions

61 interactions

InteractorPartnerSourcesPublicationsLink
CCKN_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
CCKN_HUMANCBX4_HUMANIntAct32814053 details
CCKN_HUMANSYMPK_HUMANIntAct32814053 details
CCKN_HUMANEP2A2_HUMANIntAct32814053 details
CCKN_HUMANEPM2A_HUMANIntAct32814053 details
CCKN_HUMANUB2G1_HUMANIntAct32814053 details
CCKN_HUMANRS4X_HUMANIntAct32814053 details
CCKN_HUMANRHEB_HUMANIntAct32814053 details
CCKN_HUMANRGR_HUMANIntAct32814053 details
CCKN_HUMANTF65_HUMANIntAct32814053 details
CCKN_HUMANPRPH2_HUMANIntAct32814053 details
CCKN_HUMANPTN4_HUMANIntAct32814053 details
CCKN_HUMANCXCL7_HUMANIntAct32814053 details
CCKN_HUMANPPARA_HUMANIntAct32814053 details
CCKN_HUMANNFYB_HUMANIntAct32814053 details
CCKN_HUMANMYC_HUMANIntAct32814053 details
CCKN_HUMANCITE1_HUMANIntAct32814053 details
CCKN_HUMANHELLS_HUMANIntAct32814053 details
CCKN_HUMANCCHL_HUMANIntAct32814053 details
CCKN_HUMANGABP1_HUMANIntAct32814053 details
CCKN_HUMANFYN_HUMANIntAct32814053 details
CCKN_HUMANZN333_HUMANIntAct32814053 details
CCKN_HUMANSPY4_HUMANIntAct32814053 details
CCKN_HUMAN3BP5L_HUMANIntAct32814053 details
CCKN_HUMANLPAL2_HUMANIntAct32814053 details
CCKN_HUMANSPSB1_HUMANIntAct32814053 details
CCKN_HUMANZC21C_HUMANIntAct32814053 details
CCKN_HUMANLHX5_HUMANIntAct32814053 details
CCKN_HUMANANKE1_HUMANIntAct32814053 details
CCKN_HUMANSPRY7_HUMANIntAct32814053 details
CCKN_HUMANNAGK_HUMANIntAct32814053 details
CCKN_HUMANSLN12_HUMANIntAct32814053 details
CCKN_HUMANESRP1_HUMANIntAct32814053 details
CCKN_HUMANWBP1L_HUMANIntAct32814053 details
CCKN_HUMANATL4_HUMANIntAct32814053 details
CCKN_HUMANBRWD1_HUMANIntAct32814053 details
CCKN_HUMANNUP54_HUMANIntAct32814053 details
CCKN_HUMANCIA2B_HUMANIntAct32814053 details
CCKN_HUMANVPS54_HUMANIntAct32814053 details
CCKN_HUMANAR6P4_HUMANIntAct32814053 details
CCKN_HUMANJUPI1_HUMANIntAct32814053 details
CCKN_HUMANHYPM_HUMANIntAct32814053 details
CCKN_HUMANKT222_HUMANIntAct32814053 details
CCKN_HUMANASCL4_HUMANIntAct32814053 details
CCKN_HUMANREEP6_HUMANIntAct32814053 details
CCKN_HUMANCHMP7_HUMANIntAct32814053 details
CCKN_HUMANMCFD2_HUMANIntAct32814053 details
CCKN_HUMANLEG9C_HUMANIntAct32814053 details
CCKN_HUMANH3C_HUMANIntAct32814053 details
CCKN_HUMANNUP43_HUMANIntAct32814053 details
CCKN_HUMANCP100_HUMANIntAct32814053 details
CCKN_HUMANARCH_HUMANIntAct32814053 details
CCKN_HUMANRUAS1_HUMANIntAct32814053 details
CCKN_HUMANADAL_HUMANIntAct32814053 details
CCKN_HUMANPPR21_HUMANIntAct32814053 details
CCKN_HUMANGASR_HUMANBioGRID, HPRD10438490 12695525 15001692 15068617 15520004 details
CCKN_HUMANCCKAR_HUMANBioGRID, HPRD10400673 10595537 11300760 9006937 9603948 details
CCKN_HUMANCBPE_HUMANHPRD12479974 9275097 details
CCKN_HUMANMEP1A_HUMANHPRD11278902 details
CCKN_HUMANMEP1B_HUMANHPRD11278902 details
CCKN_HUMANAMPE_HUMANHPRD8804068 details