Entity Details

Primary name CBSL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP0DN79
EntryNameCBSL_HUMAN
FullNameCystathionine beta-synthase-like protein
TaxID9606
Evidenceevidence at protein level
Length551
SequenceStatuscomplete
DateCreated2016-02-17
DateModified2021-06-02

Ontological Relatives

GenesCBSL
CBS

GO terms

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GOName
GO:0004122 cystathionine beta-synthase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006535 cysteine biosynthetic process from serine
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019346 transsulfuration
GO:0020037 heme binding
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:0070814 hydrogen sulfide biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000644 CBS domainDomainDomain
IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment siteSiteBinding site
IPR001926 Pyridoxal-phosphate dependent enzymeDomainDomain
IPR005857 Cystathionine beta-synthaseFamilyFamily
IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzymeFamilyHomologous superfamily

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
CBSL_HUMANPIAS2_HUMANBioGRID, IntAct32296183 details
CBSL_HUMANZMYM5_HUMANBioGRID, IntAct32296183 details
CBSL_HUMANGALA_HUMANIntAct32814053 details
CBSL_HUMANKAT5_HUMANIntAct32814053 details
CBSL_HUMANCYH1_HUMANIntAct32814053 details
CBSL_HUMANFKBP6_HUMANIntAct32814053 details
CBSL_HUMANKAPCA_HUMANIntAct32814053 details
CBSL_HUMANFYN_HUMANIntAct32814053 details
CBSL_HUMANCTNB1_HUMANIntAct32814053 details
CBSL_HUMANKCC2A_HUMANIntAct32814053 details
CBSL_HUMANHD_HUMANHPRD, IntAct10434301 32814053 9466992 details
CBSL_HUMANVTA1_HUMANBioGRID, HPRD16189514 details
CBSL_HUMANFXR2_HUMANBioGRID, HPRD16189514 details
CBSL_HUMANHID1_HUMANBioGRID, HPRD16189514 details
CBSL_HUMANCBSL_HUMANBioGRID, HPRD11173483 11483494 12173932 16189514 19447967 21516116 21900206 25416956 details
CBSL_HUMANCBS_HUMANBioGRID, HPRD11173483 11483494 12173932 16189514 19447967 21516116 21900206 25416956 details
CBSL_HUMANHGS_HUMANBioGRID19019082 details
CBSL_HUMANKAP0_HUMANBioGRID21900206 details
CBSL_HUMANCERT_HUMANBioGRID19447967 details
CBSL_HUMANDAXX_HUMANBioGRID21988832 details
CBSL_HUMANUGPA_HUMANBioGRID21988832 details
CBSL_HUMANPIAS1_HUMANBioGRID17087506 details
CBSL_HUMANPIAS3_HUMANBioGRID17087506 details
CBSL_HUMANUBC9_HUMANBioGRID17087506 25416956 32296183 details
CBSL_HUMANRANB9_HUMANBioGRID17087506 details
CBSL_HUMANCBX4_HUMANBioGRID17087506 details
CBSL_HUMANECHP_HUMANBioGRID25416956 details
CBSL_HUMANPIN1_HUMANBioGRID25416956 details
CBSL_HUMANAAKG1_HUMANBioGRID25416956 details
CBSL_HUMANPSA1_HUMANBioGRID25416956 details
CBSL_HUMANUBS3A_HUMANBioGRID25416956 details
CBSL_HUMANZDH17_HUMANBioGRID24705354 details
CBSL_HUMANNTAQ1_HUMANBioGRID27107012 details
CBSL_HUMANOGT1_HUMANBioGRID32994395 details