Entity Details
| Primary name |
LIPP_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P16233 |
| EntryName | LIPP_HUMAN |
| FullName | Pancreatic triacylglycerol lipase |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 465 |
| SequenceStatus | complete |
| DateCreated | 1990-04-01 |
| DateModified | 2021-06-02 |
Subcellular Location
Show/Hide Table
| Subcellular Location |
| Secreted |
Domains
Show/Hide Table
| Domain | Name | Category | Type |
| IPR000734 | Triacylglycerol lipase family | Family | Family |
| IPR001024 | PLAT/LH2 domain | Domain | Domain |
| IPR002331 | Pancreatic lipase | Family | Family |
| IPR013818 | Lipase/vitellogenin | Domain | Domain |
| IPR016272 | Lipase, LIPH-type | Family | Family |
| IPR029058 | Alpha/Beta hydrolase fold | Family | Homologous superfamily |
| IPR033906 | Lipase, N-terminal | Domain | Domain |
| IPR036392 | PLAT/LH2 domain superfamily | Family | Homologous superfamily |
Diseases
Show/Hide Table
| Disease ID | Source | Name | Description |
| 614338 | OMIM | Pancreatic lipase deficiency (PNLIPD) | An autosomal recessive disorder characterized by exocrine pancreatic failure. Clinical findings include oily/greasy stools from infancy or early childhood, absence of discernible pancreatic disease, and significantly decreased pancreatic lipolytic activity. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
Show/Hide Table
| Drug | Name | Source | Type |
| DB01083 | Orlistat | Drugbank | small molecule |
| DB02451 | B-nonylglucoside | Drugbank | small molecule |
| DB04233 | (Hydroxyethyloxy)Tri(Ethyloxy)Octane | Drugbank | small molecule |
| DB06586 | Cetilistat | Drugbank | small molecule |
| DB08222 | METHOXYUNDECYLPHOSPHINIC ACID | Drugbank | small molecule |
| DB08909 | Glycerol phenylbutyrate | Swissprot | small molecule |
Interactions
3 interactions