Entity Details

Primary name PFKAL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17858
EntryNamePFKAL_HUMAN
FullNameATP-dependent 6-phosphofructokinase, liver type
TaxID9606
Evidenceevidence at protein level
Length780
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesPFKL

GO terms

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GOName
GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005945 6-phosphofructokinase complex
GO:0006002 fructose 6-phosphate metabolic process
GO:0006096 glycolytic process
GO:0009749 response to glucose
GO:0016020 membrane
GO:0016208 AMP binding
GO:0019900 kinase binding
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0034774 secretory granule lumen
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0048029 monosaccharide binding
GO:0061621 canonical glycolysis
GO:0070061 fructose binding
GO:0070062 extracellular exosome
GO:0070095 fructose-6-phosphate binding
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000023 Phosphofructokinase domainDomainDomain
IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-typeFamilyFamily
IPR015912 Phosphofructokinase, conserved siteSiteConserved site
IPR022953 ATP-dependent 6-phosphofructokinaseFamilyFamily
IPR035966 Phosphofructokinase superfamilyFamilyHomologous superfamily
IPR041914 ATP-dependent 6-phosphofructokinase, vertebrate-typeFamilyFamily

Diseases

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