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Entity Details
Primary name
TLX1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P31314
EntryName
TLX1_HUMAN
FullName
T-cell leukemia homeobox protein 1
TaxID
9606
Evidence
evidence at protein level
Length
330
SequenceStatus
complete
DateCreated
1993-07-01
DateModified
2021-06-02
Ontological Relatives
Genes
TLX1
GO terms
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GO
Name
GO:0000785
chromatin
GO:0000978
RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228
DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634
nucleus
GO:0006357
regulation of transcription by RNA polymerase II
GO:0048513
animal organ development
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR001356
Homeobox domain
Domain
Domain
IPR009057
Homeobox-like domain superfamily
Family
Homologous superfamily
IPR017970
Homeobox, conserved site
Site
Conserved site
IPR020479
Homeobox domain, metazoa
Domain
Domain
IPR042247
T-cell leukemia homeobox protein 1/2/3
Family
Family
Diseases
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Drugs
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Interactions
14 interactions
Interactor
Partner
Sources
Publications
Link
TLX1_HUMAN
MEIS1_HUMAN
HPRD, UniProt
11342305
19559479
details
TLX1_HUMAN
MEIS2_HUMAN
UniProt
19559479
details
TLX1_HUMAN
PBX1_HUMAN
UniProt
19559479
details
TLX1_HUMAN
PBX2_HUMAN
UniProt
19559479
details
TLX1_HUMAN
PBX3_HUMAN
UniProt
19559479
details
TLX1_HUMAN
PP2AA_HUMAN
BioGRID, HPRD
9009195
details
TLX1_HUMAN
PP2AB_HUMAN
BioGRID
9009195
details
TLX1_HUMAN
PP1G_HUMAN
BioGRID
19250647
9009195
details
TLX1_HUMAN
TLE1_HUMAN
BioGRID
19250647
details
TLX1_HUMAN
PP1B_HUMAN
HPRD
9009195
details
TLX1_HUMAN
ETS1_HUMAN
IntAct
22516263
details
TLX1_HUMAN
PKNX1_HUMAN
HPRD
11342305
details
TLX1_HUMAN
TLX1_HUMAN
HPRD
16357834
details
TLX1_HUMAN
NFIC_HUMAN
HPRD
10327073
details
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