Entity Details

Primary name DUT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP33316
EntryNameDUT_HUMAN
FullNameDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length252
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesDUT

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001889 liver development
GO:0003723 RNA binding
GO:0004170 dUTP diphosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006139 nucleobase-containing compound metabolic process
GO:0006226 dUMP biosynthetic process
GO:0006260 DNA replication
GO:0014070 response to organic cyclic compound
GO:0015949 nucleobase-containing small molecule interconversion
GO:0030547 signaling receptor inhibitor activity
GO:0032556 pyrimidine deoxyribonucleotide binding
GO:0042802 identical protein binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043254 regulation of protein-containing complex assembly
GO:0046081 dUTP catabolic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR008181 Deoxyuridine triphosphate nucleotidohydrolaseFamilyFamily
IPR029054 dUTPase-likeDomainDomain
IPR033704 dUTPase, trimericDomainDomain
IPR036157 dUTPase-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03413 Deoxyuridine-5'-DiphosphateDrugbanksmall molecule
DB04685 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONEDrugbanksmall molecule