Entity Details

Primary name CD80_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP33681
EntryNameCD80_HUMAN
FullNameT-lymphocyte activation antigen CD80
TaxID9606
Evidenceevidence at protein level
Length288
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCD80

GO terms

Show/Hide Table
GOName
GO:0001618 virus receptor activity
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0009967 positive regulation of signal transduction
GO:0009986 cell surface
GO:0015026 coreceptor activity
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0031295 T cell costimulation
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032743 positive regulation of interleukin-2 production
GO:0035556 intracellular signal transduction
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897 positive regulation of protein kinase B signaling
GO:0071222 cellular response to lipopolysaccharide
GO:0098636 protein complex involved in cell adhesion

Subcellular Location

Show/Hide Table
Subcellular Location
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013162 CD80-like, immunoglobulin C2-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037676 CD80, IgC-like domainDomainDomain
IPR042711 CD80, immunoglobulin variable domainDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01281 AbataceptDrugbankbiotech
DB04901 GaliximabDrugbankbiotech
DB06681 BelataceptDrugbankbiotech

Interactions

6 interactions